Assessing Risk Mitigation Measures for People with Substance Use Disorders to Address the Double Public Health Crisis of COVID-19 and Overdose in British Columbia: A Methodical Study Protocol mixed
This article was originally published here
BMJ Open. Jun 9, 2021; 11 (6): e048353. doi: 10.1136 / bmjopen-2020-048353.
INTRODUCTION: The COVID-19 pandemic was preceded by an ongoing overdose crisis and linked to escalating drug overdose deaths in British Columbia (BC). At the start of these two public health emergencies, the British Columbia government announced Interim Risk Mitigation Guidelines (RMGs) that allowed for the prescription of drugs that are alternatives to substances, including opioids, alcohol, stimulants. and benzodiazepines, an intervention sometimes referred to as a “safe supply”. This protocol describes the approach of a study of the implementation of RMG and its impacts on COVID-19 infection, drug-related and systemic harms, continuity of care for people with disorders related to substance use (SUD), as well as their behavior, psychosocial and well-being outcomes.
METHODS AND ANALYSIS: We conducted a parallel mixed-methods study that involved both population-level administrative health data analysis and primary data collection, including a 10-week longitudinal observational study ( target n = 200), a cross-sectional survey (target n = 200) and qualitative interviews (target n = 60). We implemented a participatory approach to this assessment, in partnership with people with lived or living expertise in drug use, as well as researchers and public health decision-makers from across the province. Population-level linked administrative databases will analyze data from a cohort of BC residents with an indication of SUD between 1996 and 2020. We will perform high-dimensional propensity score matching and structural modeling. marginale to build a control group and assess the impact of RMG. receipt of exemption on a set of primary and secondary results determined in collaboration.
ETHICS AND DISSEMINATION: Study activities were developed to adhere to the Tri-Council Policy Statement: The Ethical Conduct of Research Involving Humans, Recommended Research Practices on COVID-19, and Guided by Calls to the action of the Truth and Reconciliation Commission for public health, data governance and research ethics related to indigenous peoples. The results will be disseminated gradually, on an ongoing basis, through the consortium established for this study, and then published in peer-reviewed journals.